A qualitative, semi-structured interview study was conducted, involving cancer patients who had received a VUS result through the Cancer Genetics Service of the National Cancer Centre Singapore. This exploratory study aims to investigate the experience of Asian cancer patients upon receiving a VUS result. Managing VUS results presents challenges, as it often leads to increased anxiety and distress among cancer patients undergoing genetic testing. , Carcinoma, Intraductal, Noninfiltrating/pathologyĭue to a lack of ancestry-matched, functional, and segregation data, Asians have a higher rate of receiving a variant of uncertain significance (VUS) result following panel testing. , Carcinoma, Intraductal, Noninfiltrating/therapy , Carcinoma, Intraductal, Noninfiltrating/diagnosis , Carcinoma, Intraductal, Noninfiltrating On long-term follow-up, mode of presentation was not statistically associated with recurrence. Symptomatic patients tend to be associated with grade III tumours, compared to non-symptomatic patients. CONCLUSION: Young women with DCIS tend to present with symptoms, with breast lump as the commonest symptom. On median follow-up of 85 months, there were 3 (7.3%) recurrences, which were not statistically associated with presentation mode. Cases presenting with symptoms were statistically associated with higher grade (p = 0.0090). The average tumor size was 22.0 mm (range 2.0-86.9) and 12.2 mm (range 3-25) for patients who presented with symptoms and non-symptomatic group, respectively. Of the cases who presented with symptoms, 86.7%, 10.0% and 3.3% had palpable lump, nipple discharge or breast pain, respectively. 73.2% and 26.8% presented with symptoms or abnormal imaging respectively. The mean age at diagnosis was 32.3 years (range 17-39). RESULTS: 40 patients with 41 cases were included. Statistical analysis was performed to investigate the correlation of presentation mode with outcomes. Clinical presentation, pathology and recurrence data were collected. METHODS: Pure DCIS patients aged <40 years were retrospectively analyzed. We aimed to compare characteristics of DCIS patients <40 years of age presenting with symptoms versus those without, and determine whether presentation mode affects recurrence. Young women have also been associated with poorer outcomes, but it is unknown whether presentation mode affects outcome. Since they do not qualify for mammographic screening, they are more likely to present with symptoms. Siew, Sara Phui Yee.INTRODUCTION: Ductal carcinoma in situ (DCIS) in young women is rare and not well studied. Goh, Su Xin.Īw, Wendy Wen Ting Cheng, Mark Chun Yeong Chew, Eunice Yixian Tan, Li Shan Who nose what eye can see? : examining the impact of scent on visual attentionĬhong, Trinetta Chiao Sing. When should organizations apologize in times of crises? : examining how the timing of apologies, prior reputation and procedural justice influence stakeholders’ perceptions, attitudes and behavioral responsesĬheng, Brinda Shu Yu Ho, Benjamin Meng-Keng Nur Aini Malik Fadjiar Lau, Liang Tong Unplug! world wider than WWW : a campaign addressing internet dependency amongst youth in SingaporeĬhew, Wen Jing Lim, Xinyi Loh, Cheryl Quee, Yan Jing Television food advertising towards children : a content analysis of the Singapore advertising landscape and experimental study on the placement of pro-nutritional advertisements Tran, Khanh Phuong Chia, Cathy Wei Si Ng, Felicia Su Hway Tapping informal networks “Guanxi” with information and communication technologies : empowering rural doctors in Xi’an, China Social cues & cyberbullying in facebook : the effects of flaming messages, friend count and anonymity on cyberbullying behaviorsĬhan, Hui Ling Kok, Yinghui Ong, Jeremy Yuvitasari, Fitrina Low, Hee Ann Quek, Hui Ying Tan, Wei Yuan Ng, Wilson Kok Jung Reclaim land : the fight for space in Singapore Project gad-savvy : a health communications campaign educating tertiary students in Singapore about gadget dependency Low, Jin Yong Tan, Adeline Darwitan, Andrew Ng, Kaijie Planting the green idea : a study of medium effectiveness on behavioural intentions using the theory of planned behaviour Koay, Jing Li Ng, Janissa Sihui Wong, Gladys Li Chieh Nintendo Wii as an intervention : improving the well-being of elderly in long-term care facilities Naturally overused : an analysis of health claims on "healthy" supermarket food products with an emphasis on the "natural" angleĬhua, Joanne Wanlin Ho, Eunice Jia Hui Klyne, Mary Ann
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